Sjogren’s Syndrome

What is Sjogren’s Syndrome?

Sjogren's Syndrome is a chronic autoimmune disorder in which the body's immune system mistakenly attacks its own moisture-producing glands. This primarily affects the salivary glands (leading to dry mouth) and the lacrimal glands (leading to dry eyes). However, it can also affect other parts of the body, including the joints, thyroid, kidneys, liver, lungs, digestive system, vagina, skin, and nerves.

Types of Sjogren’s Syndrome

Physicians categorize Sjogren’s syndrome into two types:

  • Primary Sjogren’s syndrome develops on its own and is not caused by another health condition. It tends to be more aggressive and can cause more dryness.
  • Secondary Sjogren’s syndrome develops when another autoimmune disease causes Sjogren’s syndrome.

Causes of Sjogren Syndrome

The exact cause of Sjogren's Syndrome is not known, but it is believed to result from a combination of genetic, environmental, and possibly hormonal factors. It often occurs in people with other autoimmune diseases, such as rheumatoid arthritis or lupus.

Symptoms of Sjogren Syndrome

Symptoms of Sjogren's syndrome can include:

  • Dry eyes (feeling gritty or burning)
  • Dry mouth (difficulty swallowing, speaking, or tasting)
  • Swollen salivary glands
  • Dry skin
  • Joint pain and stiffness
  • Persistent dry cough
  • Fatigue

Diagnosis of Sjogren Syndrome

Diagnosing Sjogren's syndrome can be challenging because its symptoms overlap with many other conditions. Tests that may be used include:

  • Blood tests to check for specific antibodies.
  • Eye tests to measure tear production (Schirmer's test) and the health of the cornea.
  • Salivary gland tests, including imaging and biopsy.

Treatment for Sjogren’s Syndrome

There is no cure for Sjogren's syndrome, but treatment focuses on relieving symptoms and preventing complications. This may include:

  • Artificial tears and saliva substitutes
  • Medications to increase saliva production (such as pilocarpine or cevimeline)
  • Anti-inflammatory medications for joint pain
  • Immunosuppressive drugs in severe cases
  • Regular dental care to prevent tooth decay and infections
  • Vaginal lubricants for vaginal dryness
  • Prescription expectorants and throat medications in cases of respiratory dryness

Management

Patients with Sjogren's Syndrome can manage their condition by:

  • Staying hydrated.
  • Using humidifiers to add moisture to the air.
  • Avoiding smoking and alcohol, which can worsen dryness.
  • Practicing good oral hygiene.
  • Using eye drops or ointments to keep eyes moist.

Regular follow-ups with healthcare providers are important to monitor and manage symptoms and any potential complications.